Weight-Loss Drugs Explained: Ozempic, Wegovy, Mounjaro

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What it is

These are prescription medicines originally developed for type 2 diabetes. For weight management, they help reduce appetite and caloric intake. Brand names you may hear: Ozempic and Wegovy (semaglutide) and Mounjaro (tirzepatide). Doctors prescribe them based on health history, other medications, and treatment goals.

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How they work

• Hormone mimic. They act like gut hormones (GLP-1; and for tirzepatide, GLP-1 + GIP) that signal fullness and slow stomach emptying.
• Less intake. People tend to eat smaller portions and snack less.
• Ongoing use. Benefits usually depend on continued treatment plus behavior changes.

Why it matters

Many adults struggle with weight-related conditions. These drugs can improve outcomes when used appropriately, but they raise questions about side effects, long-term plans, and affordability. Always discuss personal risks with a clinician.

Risks and side effects

• Common: nausea, vomiting, diarrhea, constipation—often lessen over time.
• Less common but serious: certain digestive or gallbladder issues; rare risks are monitored. Not for pregnancy. Check official prescribing information.
• Interactions: may interact with other medicines and conditions. Medical guidance is required.

Access and cost

They require a prescription. Coverage and cost vary by country, insurer, and indication (diabetes vs. obesity). Supply can fluctuate. Ask your provider and insurer about eligibility, coverage criteria, and alternatives.

What to ask your doctor

• Is this appropriate for my health history and current medications?
• What side effects should I watch for, and how are they managed?
• How long might I stay on it, and what is the plan if I stop?
• What lifestyle changes will support results and reduce regain?

Sources

• FDA
• EMA
• WHO — Obesity

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